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Symposium

Child / Adolescent - Depression
Symposium

Symposium 40 - Prevention of Adolescent Depression in Primary Care Settings: Design, Methods, and Preliminary Findings of the Path 2 Purpose (P2P) Study.

Saturday, June 27, 2026
2:00 PM - 3:30 PM PDT
Location: Yerba Buena Salon 14, B3 Level
CE: 1.5

Keywords: Depression, Adolescents, Prevention
Level of Familiarity: Basic to moderate
Recommended Readings: Batterham, P. et al. (2025). Future directions in depression prevention. Journal of Consulting and Clinical Psychology, 93 (4), 328-339.,   Brunweasser, S. & Garber, J. (2016). Programs for the prevention of youth depression: Evaluation of efficacy, effectiveness, and readiness for dissemination. Journal of Clinical Child and Adolescent Psychology,45 (6), 763-783.,   Dickerson, J. et al. (2024). Cognitive Behavioral program for the prevention of depression in at-risk adolescents: Isolating the effects of dose. American Journal of Epidemiology, kwae131,   Garber, J. et al. (2009). Prevention of depression in at-risk adolescents: A randomized controlled trial. JAMA, 301 (21), 2215-2224.,   Saulsberry, A. et al., (2013). Randomized clinical trial of a primary care internet-based intervention to prevent adolescent depression: One year outcomes. Journal of the Canadian Academy of Child and Adolescent Psychiatry, 22 (2), 106-117.

In this symposium we describe the rationale, design, methods, and report preliminary findings from the Path to Purpose (P2P) Study. Completed at 32 clinical sites, this RCT examined the short- and long-term effectiveness of two CBT-based depression prevention programs, Teens Achieving Mastery over Stress (TEAMS; Online, group CBT) and Competent Adult Transition with Cognitive-Behavioral, Humanistic, and Interpersonal Training (CATCH-IT; Online modular CBT). Participants included 536 13-17 year-old youth recruited through primary care settings. Teens were at-risk for experiencing a Major Depressive episode. Stratified cluster randomization was completed at the clinic level, with controls for SES, race-ethnicity, rural-urban, and level of community distress. Results indicate that incidence of a depressive episode at 6-months follow-up was 9.6% for CATCH-IT and 7.2% for TEAMS. GAS scores improved significantly from baseline for both groups. No moderators of time-to-episode or GAS were found.

Learning Objectives:

  • The importance of offering youth depression prevention programs in primary-care settings
  • Components of online modular- and group-based CBT depression prevention protocols
  • Factors facilitating teen engagement with online prevention programs
  • Preliminary findings regarding the acceptability and effectiveness of online CBT prevention programs
  • Findings presented by the WHO indicate that Major Depression is a leading cause of clinical morbidity and mortality worldwide. At the same time, adolescent depression and suicide are increasingly important clinical and social concerns. With this in mind, participants will be able to describe, discuss, and advocate for the development of evidence-based teen depression prevention programs. Dissemination of CBT into community settings, such as pediatricians offices, and making them both accessable and engaging to teens and families, is a priority.

Presentations:

  • 2:03 PM - 2:30 PM PDT
    (SYM40) Prevention of Adolescent Depression in Primary Care Settings: Design and Methods of the Path to Purpose (P2P) Study

    Author: Mark A. Reinecke, PhD, ABPP, ACBT

  • 2:30 PM - 2:57 PM PDT
    (SYM40) Comparative Effectiveness of Two Evidence-based Depression Prevention Programs With at-risk Youth: Preliminary Outcomes.

    Presenter: Tracy Gladstone, Ph.D. – Brown University

    Co-Presenter: Benjamin Van Voorhees, MD, MPH – University of Illinois at Chicago

    Co-Presenter: Mark A. Reinecke, PhD, ABPP, ACBT

  • 2:57 PM - 3:30 PM PDT
    (SYM40) Prevention of Adolescent Depression in Primary Care Settings: What Do We Know? What Do We Need?

    Presenter: Benjamin Van Voorhees, MD, MPH – University of Illinois at Chicago

    Co-Presenter: Tracy Gladstone, Ph.D. – Brown University

    Co-Presenter: Mark A. Reinecke, PhD, ABPP, ACBT